Downregulation of surface AMPA receptor expression in the striatum following prolonged social isolation, a role of mGlu5 receptors

Major depressive disorder is a common and serious mood illness.The molecular mechanisms underlying the pathogenesis and symptomatology of depression are poorly understood at present.Multiple neurotransmitter systems are believed to be implicated in depression.Increasing evidence supports glutamatergic transmission as a critical element in depressio

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Oculomotor deficits in aryl hydrocarbon receptor null mouse.

The Aryl hydrocarbon Receptor or AhR, a ligand-activated transcription factor, is known to mediate the toxic and Travel Essential carcinogenic effects of various environmental pollutants such as 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD).Recent studies in Caenorhabditis elegans and Drosophila melanogaster show that the orthologs of the AhR are expr

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Improved survival following ward-based non-invasive pressure support for severe hypoxia in a cohort of frail patients with COVID-19: retrospective analysis from a UK teaching hospital

Since the outbreak of COVID-19 in China in December 2019, a pandemic has rapidly developed on a scale that has overwhelmed health services in a number of countries.COVID-19 has the potential to lead to severe hypoxia; this is usually the cause of death if it occurs.In a substantial number of patients, adequate arterial oxygenation cannot be achieve

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Double-Needle Arthrocentesis with Viscosupplementation in Patients with Temporomandibular Joint Disc Displacement without Reduction

OBJECTIVES: Arthrocentesis is the simplest surgical intervention for the temporomandibular joint (TMJ).It can be performed on an outpatient basis at a low cost and with low morbidity.The objective is to release the articular disc by disrupting the adhesion formed between its surfaces and the mandibular fossa through hydraulic pressure generated by

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